Serrapeptase Health Benefits and Uses

Claims about the beneficial effects of serrapeptase are still inconclusive but studies show that it may have positive effects on cardiovascular health.

Serrapeptase from silkworms

Today, about millions of Americans are using serrapeptase and health experts in Europe are prescribing it as food supplements. Research shows that it has the same anti-inflammatory effects like ibuprofen and aspirin and it could be a safer alternative for stronger painkillers.

What is Serrapeptase?

Serrapeptase is a proteolytic enzyme or protease that is harvested from a silkworm; other terms used to describe this enzyme is serratiopeptidase, serralysin, Serratia peptidase, and serrapeptase. Specifically, the enzyme comes from a bacterium called Serratia that is produced from the gut of the silkworm. When the silkworm transformed into a moth, it uses the protease to break down the cocoon. The enzyme is isolated and manufactured into tablets. It is known to have loads of beneficial effects from anti-inflammatory to improving cardiovascular health. As mentioned, it has anti-inflammatory effects like ibuprofen.

Claims about the beneficial effects of serrapeptase are still inconclusive but studies show that patients who ingested serrapeptase, though the inflammation wasn’t completely eliminated, it significantly improved the person’s condition.

Further research also shows it reduces the risks of cardiovascular-related illnesses from occurring. It hinders plaque accumulation in the arteries that cause a stroke or heart attack.

Overview of how serrapeptase works:

  • Reduces the fluid causing the inflammation and supports faster tissue repair.
  • Neutralizes the release of bradykinin in the bloodstream that is triggering the pain sensation.
  • Breaks down the protein that accumulates in the arteries to prevent stroke or heart attack.

Uses and Health Benefits

Although the natural role of serrapeptase is to break down the cocoon for the moth to break free, researchers observed that the bacteria present in the enzyme also has positive effects in the human body.

One of the primary uses of serrapeptase is as an anti-inflammatory medication. It is used to relieved pain from migraine, tension headache, back pains, and rheumatoid arthritis. It also relieves pain from osteoporosis experiencing by the elderly.

When this enzyme is released into the bloodstream it enhances the immune system and reduces the production of bradykinin and fluids that cause inflammation. At the same time, it promotes tissue repair for faster healing from injuries.

There is no known potential risk linked to serrapeptase and reports of overdosage. However, it is still advisable to consult your doctor or a health professional before including serrapeptase in your daily medications.

Reduces mucus production

It dissolves mucus and eliminates the bacteria causing its production. Experts suggest that an approximate of 30mg per day for 4 weeks may completely treat the sinus problem. They also observed that the frequency of coughing and sinus problems have decreased in people having a daily intake of serrapeptase.

Anti-inflammatory and painkillers

This anti-inflammatory medication is in circulation for 30 years in Asian and European countries; the preferred painkillers by doctors because it is less risky and the health benefits linked to it.

It works by reducing the production of a certain kind of fluid that causes inflammation and neutralizes a chemical called bradykinin which is responsible for the pain response of the body. At the same time, it enhances the immune cells that heal the injured tissues.

Inflammation is a natural defense mechanism by the body from infections and it is accompanied by mild to searing pain sensations. Daily intake of serrapeptase promotes tissue health and increases its defense from inflammatory molecules that reduce pain levels.

It is known to heal inflammation from:

  • Muscle and back pains
  • Arthritis
  • Wounds
  • Sinusitis
  • Heart conditions

A study also shows that serrapeptase lowers chances of night cramps by fifty percent. And if it occurs, the pain is reduced by sixty percent.

Cardiovascular health

A study suggests that serrapeptase lowers the risks of any heart disease and stroke by breaking down protein accumulation in the arteries.

Serrapeptase is gaining a reputation for its beneficial effects on the heart, but the results of the study were inconclusive and extensive research has to be made about its effectivity in improving cardiovascular health.

Still, the best way to properly care your heart is to have a healthy lifestyle—minimize consummation of foods high in cholesterol and fats. Instead, eat more foods rich in vitamins and nutrient; and if you are feeling any chest pain and in suspicion of a heart condition, the best way is to consult your doctor.

Heals scarred tissues

Scars are the result of a protein called fibrin. A study shows that serrapeptase breaks down these proteins and allows the tissues to heal.

Enhance antibiotic effectiveness

When antibiotics are paired with serrapeptase it improves the effectiveness of antibiotics by breaking down dead tissues allowing antibiotics to work faster. And combining antibiotics with serrapeptase is safe and possess no risk.

An increase in sperm count

Research suggests that serrapeptase may increase sperm count. The research was made on fifty infertile male patients; they were given a combination of serrapeptase and quinolones. After a few weeks, twenty-two male showed signs of an increase in sperm count.


Research suggests that an average of 10 to 30mg per day is enough to gain its full benefit. However, this study is irrelevant since it didn’t definitively conclude the potency of this enzyme and its molecular activity. Unlike dietary supplements that depend on its effectiveness on the amount of intake, serrapeptase base its effectiveness on the strength of the enzyme. This means that the dosage will depend on a person’s needs and how his body would react.

For example, a person experiencing joint pains may need 350,000 SU’s per day to relieve pain but another person may need 550,000 SU’s per day. Consult a health professional to know how much dosage you need daily.

The enzymes present in serrapeptase will work on the biochemical make-up of a person and unlikely to depend on a person’s weight.

SU means serrapeptase units. But you may find other terms like SPU, which means serratiopeptidase units. The two terms are the same and can be used vice versa.


There are no known risks to overdosage of serrapeptase and no cases that are associated with serrapeptase overdosage. However, its effectiveness is also in question since the studies were inconclusive and show little evidence on its potency.

If you are considering serrapeptase, consult your doctor first or a health care professional.

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